Case of June 2021

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Clinical History:

A 44 year-old male with known history with mixed diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma with multiple cervical lymphadenopathy was given 6 cycles of combined cytoreductive targeted therapy and chemotherapy. Two months after chemotherapy he developed fever, shortness of breath despite antiviral drugs and empirical antibiotics. Initial investigations show moderate leukopenia (WBC count 1.7 x 10⁹/L) with mild neutropenia (1.3 x 10⁹/L) and moderate lymphopenia 0.3 x 10⁹/L). Urgent computed tomography (CT) was arranged in view of persistent fever and desaturation.