Clinical History
A 70-years-old lady with history of arrhythmia presented with shortness of breath. HRCT of the thorax was obtained.
Diagnosis:
Amiodarone-induced lung fibrosis
Comment :
HRCT thorax showed architectural distortion with interlobular septal
thickening and traction bronchiectasis in both lungs, predominantly basal
and peripheral in distribution. It is most severe in left lung base with
honeycomb appearance. Findings are compatible with pulmonary fibrosis.
Cardiomegaly was an additional finding.
Nonenhanced abdominal CT scan showed high attenuation of the liver (86HU)
relative to that of the spleen (43HU), indicating abnormally hyperdense
hepatic parenchyma. The patient was actually receiving amiodarone for cardiomyopathy and arrhythmia and the overall picture is compatible with
amiodarone-induced lung fibrosis and hyperdense liver. |
